Skip to main content

Table 3 The association analysis between NSE and SCC

From: The important role of circulating CYFRA21-1 in metastasis diagnosis and prognostic value compared with carcinoembryonic antigen and neuron-specific enolase in lung cancer patients

 

No. (%)

  

Neg

Moderate

High

Total

P Value

 

(1–2 fold)

>2 fold

  

(n = 110)

(n = 70)

(n = 35)

(n = 215)

 

Basic Characteristics

 Age

   < 45 years

3 (2.7)

2 (2.9)

0 (0.0)

5

0.622

  45–60 years

40 (36.4)

23 (32.8)

9 (25.7)

72

   > 60 years

67 (60.9)

45 (64.3)

26 (74.3)

138

 Sex

  Male

101 (91.8)

61 (87.1)

30 (85.7)

192

0.463

  Female

9 (8.2)

9 (12.9)

5 (14.3)

23

 Stages

  I + II

26 (23.6)

6 (8.6)

1 (2.8)

33

<0.05*

  III + IV

80 (72.7)

62 (88.6)

33 (94.4)

175

  Unknown

4 (3.7)

2 (2.8)

1 (2.8)

7

 Smoke status

  No

22 (20.0)

16 (22.9)

9 (25.7)

47

0.753

  Yes

88 (80.0)

54 (77.1)

26 (74.3)

168

Metastasis

 Brain

  No

107 (97.3)

62 (88.6)

27 (77.1)

196

<0.05*

  Yes

3 (2.7)

8 (11.4)

8 (22.9)

19

 Bone

  No

100 (90.9)

55 (78.6)

27 (77.1)

182

<0.05*

  Yes

10 (9.1)

15 (21.4)

8 (22.9)

33

 Liver

  No

102 (92.7)

61 (87.1)

27 (77.1)

190

0.062

  Yes

8 (7.3)

9 (12.9)

8 (22.9)

25

 Adrenal gland

  No

106 (96.4)

64 (91.4)

32 (91.4)

202

0.316

  Yes

4 (3.6)

6 (8.6)

3 (8.6)

13

 Lymph node

  No

51 (46.4)

19 (27.1)

9 (25.7)

79

<0.05*

  Yes

59 (53.6)

51 (72.9)

26 (74.3)

136

 Intrapulmonary

  No

96 (87.3)

58 (82.9)

31 (88.6)

185

0.632

  Yes

14 (12.7)

12 (17.1)

4 (11.4)

30

 Pleural

  No

98 (89.1)

59 (84.3)

31 (88.6)

188

0.622

  Yes

12 (10.9)

11 (15.7)

4 (11.4)

27

 Mediastinal

  No

108 (98.2)

61 (87.1)

34 (97.1)

203

<0.05*

  Yes

2 (1.8)

9 (12.9)

1 (2.9)

12

 Peritoneum

  No

109 (99.1)

61 (87.1)

31 (88.6)

201

<0.05*

  Yes

1 (0.9)

9 (12.9)

4 (11.4)

14

  1. *p < 0.05, **p < 0.001