Fig. 3

Phylogenetic analyses. a Cluster analysis of the point mutations in each cancer component. The mutation data were standardized and presented as a heat map. Column next to heatmap shows the mutated genes and amino acid changes. b The phylogenetic tree was constructed by an approach using the bootstrap. Branch lengths correlates with the number of nucleotide substitutions. Abbreviations: Non mut, non-mutated cells; Well, well-differentiated adenocarcinoma; Poor, poorly differentiated adenocarcinoma; Sarco, sarcomatoid carcinoma