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Table 2 Univariate and multivariate analyses of clinicopathological features and overall survival rate of patients enrolled in the study

From: Discoidin domain receptor 1 activity drives an aggressive phenotype in gastric carcinoma

 

Univariate analysis

Multivariate analysis

Total

No adjuvant

Adjuvant

Total

No adjuvant

Adjuvant

Mean ± SD

P value

Mean ± SD

P value

Mean ± SD

P value

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

Age

<70

80.0 ± 2.8

0.019

82.5 ± 3.6

0.028

76.5 ± 3.4

0.016

1

<0.001

  

1

0.002

≥70

67.2 ± 4.7

78.2 ± 6.1

52.0 ± 5.2

2.6 (1.6–4.4)

2.5 (1.4–4.5)

Gender

Male

74.1 ± 3.1

0.092

79.7 ± 4.6

0.027

70.6 ± 3.9

0.346

1.8 (1.0–3.3)

0.048

    

Female

75.7 ± 3.7

NR

70.5 ± 4.8

Location

Upper

78.8 ± 7.1

0.109

66.1 ± 11.4

0.961

77.2 ± 8.1

0.130

      

Middle

81.8 ± 3.5

86.3 ± 4.7

76.2 ± 4.5

Low

80.0 ± 2.5

78.1 ± 4.5

61.3 ± 3.5

Lauren

Intestinal

78.0 ± 3.6

0.651

86.9 ± 2.5

0.374

63.7 ± 4.1

0.644

      

Mixed

73.6 ± 5.0

79.7 ± 5.0

75.1 ± 4.7

Diffuse

68.1 ± 3.6

76.2 ± 2.4

68.9 ± 6.4

Differentiation

Differentiated

84.0 ± 3.7

0.064

83.4 ± 4.9

0.571

82.9 ± 4.9

0.042

1

0.042

  

1

0.072

Undifferentiated

68.8 ± 2.9

79.3 ± 4.3

64.7 ± 3.4

1.8 (1.0–3.3)

1.9 (0.9–3.8)

T stage

T1/T2

90.3 ± 1.7

<0.001

91.6 ± 2.0

<0.001

83.9 ± 2.1

<0.001

1

<0.001

1

0.006

1

<0.001

T3/T4

60.7 ± 4.0

41.8 ± 10.3

62.0 ± 4.2

6.4 (3.8–12.1)

7.0 (1.7–28.2)

4.8 (2.1–10.8)

N stage

N0/N1

82.9 ± 2.5

<0.001

87.6 ± 3.2

0.003

75.3 ± 3.1

0.005

  

1

0.039

  

N2/N3

62.8 ± 4.5

54.7 ± 11.0

63.1 ± 4.8

4.8 (1.1–21.5)

DDR1

Negative

82.8 ± 3.3

0.015

84.7 ± 4.3

0.933

80.4 ± 4.2

0.013

    

1

0.083

Positive

66.5 ± 3.6

74.5 ± 4.6

62.2 ± 3.9

1.7 (0.9–3.0)

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BMC Cancer

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