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Table 1 Energy comparison of affinity to mTOR in two compounds

From: Cryptotanshinone activates AMPK-TSC2 axis leading to inhibition of mTORC1 signaling in cancer cells

Compound

CDOCKER Energya

CDOCKER Interaction Energya

Rapamycin

−69.294

−80.192

Cryptotanshinone

−0.443

−29.761

  1. aLess energy, more stable