From: Genetic polymorphisms of SCN9A are associated with oxaliplatin-induced neuropathy
SNP | Total nr. of patients | Cases TNS ≤ 6 (n = 48) | Controls TNS ≥ 15 (n = 46) | P value* |
---|---|---|---|---|
rs6746030 | 0.041 | |||
C/C | 64 | 23 (48%) | 41 (89%) | |
C/T | 29 | 24 (50%) | 5 (11%) | |
T/T | 1 | 1 (2%) | 0 (0%) | |
rs41268673 | 0.589 | |||
C/C | 91 | 46 (96%) | 45 (98%) | |
C/A | 3 | 2 (4%) | 1 (2%) | |
A/A | 0 | 0 (0%) | 0 (0%) | |
rs74401238 | 0.683 | |||
G/G | 89 | 45 (94%) | 44 (98%) | |
G/A | 5 | 3 (6%) | 2 (2%) | |
A/A | 0 | 0 (0%) | 0 (0%) |