Fig. 4From: Pancreatic neuroendocrine tumor with metastasis to the spleen: a case report a Histopathological findings revealed that the tumor was composed of cells with round nuclei arranged in sheets or rosettes (Hematoxylin and eosin stain × 100). b The tumor cells were weakly positive for synaptophysin by immunohistochemical staining (×100), c The chromogranin A (×100), and MIB 1 index was about 10% (d) In this case, CD56 and other immunohistochemical stains were negative except for SSTR-2 (x100)Back to article page