Table 3 Multivariate analysis: Factors predictive of All Cause mortality
From: Biopsy of breast cancer metastases: patient characteristics and survival
Variable | P value | HR Adjusted(95.0% CI for HR) | |
|---|---|---|---|
HR & HER2 at initial diagnosis | HR+/HER2+ | Ref. | |
HR-/HER2- | .002 | 2.14 (1.36–3.39) | |
HR-/HER2+ | .179 | 1.36 (0.86–2.27) | |
HR+/HER2- | .013 | 1.61 (1.11–2.29 | |
HR and/or HER2 missing | .065 | 1.49 (0.98–2.21) | |
Site of metastasis at recurrence | No brain, liver or lung metastasis | Ref. | |
Liver & lung involvement | .000 | 2.46 (1.68–3.60) | |
Brain involvement | .000 | 2.85 (1.88–4.31) | |
Age at metastatic recurrence (years) | <70 | Ref. | |
> = 70 | .002 | 1.64 (1.19–2.24) | |
Stage at initial diagnosis | Stage 0-IIA | Ref. | |
Stage IIB-III | .004 | 1.40 (1.12–1.76) | |
Biopsy | No biopsy | Ref. | |
Biopsy | .002 | 0.67 (0.52–0.86) |