Table 2 Linear regression models of associations between early life socioeconomic status and adult mammographic density, EDMD Study
From: Early life socioeconomic environment and mammographic breast density
| Â | Model 1: Adjusted for age at mammogram & adult BMI | Model 2: adjusted, for age at mammogram, adult BMI and early life factors (PTS, birthweight, weight at age 4) | Model 3:adjusted for age at mammogram, adult BMI, early life factors and adult SES (adult education & income) |
|---|---|---|---|
β (95% CI) | β (95% CI) | β (95% CI) | |
Dense area (cm2) | |||
 Maternal Education at birth | |||
  Less than high school (reference) | |||
  High school graduate | 0.01 (−4.3, 4.3) | −0.6 (−5.2, 3.9) | −1.7 (−6.3, 3.0) |
  Trade school or some college | −0.8 (−5.7, 4.2) | −2.9 (−8.0, 2.2) | −4.3 (−9.8, 1.1) |
  College graduate or higher education | 1.8 (−4.4, 8.0) | −1.4 (−8.3, 5.4) | −4.8 (−12.1, 2.4) |
Family income at birth | |||
  < $5000 (reference) | |||
 $5000-$7999 | −1.2 (−5.1, 2.7) | −1.4 (−5.4, 2.6) | −1.5 (−5.7, 2.7) |
  ≥ $8000 | −6.3 (−11.0, −1.6) | −6.9 (−11.8, −2.1) | −8.2 (−13.3, −3.2) |
Non-dense area (cm2) | |||
 Maternal education at birth | |||
  Less than high school (reference) | |||
  High school graduate | −7.7 (−18.0, 2.6) | −5.4 (−15.6, 4.8) | −5.7 (−16.5, 5.0) |
  Trade school or some college | −1.0 (−13.4, 11.4) | −3.3 (−16.1, 9.6) | −3.8 (−17.0, 9.4) |
  College graduate or higher education | −8.2 (−20.8, 4.4) | −5.5 (−19.2, 8.3) | −3.5 (−18.6, 11.5) |
 Family income at birth | |||
   < $5000 (reference) | |||
  $5000-$7999 | −4.3 (−13.2, 4.6) | −3.6 (−12.4, 5.2) | −1.9 (−11.1, 7.3) |
   ≥ $8000 | −1.9 (−13.2, 9.4) | −1.6 (−13.5, 10.2) | 0.8 (−11.4, 12.9) |
Percent density | |||
  Maternal education at birth | |||
  Less than high school (reference) | |||
  High school graduate | 1.4 (−1.4, 4.2) | 0.7 (−2.2, 3.7) | 0.4 (−2.6, 3.4) |
  Trade school or some college | 0.5 (−2.8, 3.8) | −0.2 (−3.7, 3.3) | −0.8 (−4.4, 2.9) |
  College graduate or higher education | 4.8 (0.6, 9.1) | 3.4 (−1.4, 8.2) | 1.1 (−4.0, 6.2) |
Family income at birth | |||
  < $5000 (reference) | |||
 $5000-$7999 | −0.7 (−3.2, 1.8) | −0.7 (−3.3, 1.8) | −0.9 (−3.6, 1.8) |
  ≥ $8000 | −2.6 (−6.1, 0.9) | −2.3 (−6.0, 1.4) | −3.2 (−6.9, 0.5) |