Table 3 Relation between tumor response and metabolic toxicities
CTC Grade of Toxicities | Highest change in biological parameters | Median time to CTC Grade ≥ 2 toxicities | |
|---|---|---|---|
CB (%) / PD (%) (p) | CB (%) / PD (%) (p) | CB (days) / PD (days) | |
Lymphopenia | NA / 84 (0.01) | ||
Increase in serum creatinine | 92 / 46 (0.01) | +61 / -5 (0.002) | |
Hyperglycemia | 56/112 (0.03) | ||
Hypophosphatemia | −26 / -9 (0.02) | ||
Increase in ASAT | 94 / 66 (0.04) | +126 / +8 (0.004) | |
Increase in ALAT | 100 / 66 (0.01) | +229 / +4 (0.003) | |
Hypercholesterolemia | |||
Hypertriglyceridemia |