Table 1 Use of steroids in the treatment of inoperable NICTH

Teale, et al. 1998 [18]

4

One patient was treated with dexamethasone 4 mg three times a day.

Three patients were treated with prednisolone 30 mg once daily.

6 weeks–7 months

To compare the effectiveness of hGH and glucocorticoid therapy in NICTH by analyzing the molecular distribution of different forms of IGF-II and IGFBP-3.

Teale, et al. 2004 [20]

6

Five patients were treated with prednisolone. Different regimens included: 20 mg once daily; 30 mg once daily; 5 mg three times a day)

One patient was treated with dexamethasone 4 mg once daily.

6–13 months

To compare the outcome of different treatment options in NICTH

Bourcigaux, et al. 2005 [9]

1

Three different phases of study: phase 1 with prednisone only, phase 2 with hGH only, phase 3 with both.

The lowest effective dose when steroids were used alone was prednisone 30 mg.

Days (experimental study)

To assess if combination therapy with low dose steroid and hGH is effective in inoperable patients with NICTH.

Perros, et al. 1996 [19]

1

Prednisone 30 mg once daily given with a combination of hGH and bendrofluazide; steroids were lowered later to 15 mg once daily (only in combination),

9 months

Case Report