Tumor characteristics and prognosis in familial breast cancer

BMC Cancer

Table 3 Recurrence, contralateral breast cancer and second primary rates according to BRCA status

	BRCA-positive		BRCA-wild type		Sporadic		p-value
	N	%	N	%	N	%
	N = 33		N = 66		N = 1826		<0.0001
No events	17	52	34	51	1264	69
Recurrence	9	27	22	33	522	29
Contralateral Breast	4	12	9	14	6	0
Second primary^a	3	9	1	1	34	2

The 21 patients carrying variants of unknown significance were excluded from the analysis
^aSecond primaries are defined as all non breast second primaries

ISSN: 1471-2407