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Table 4 Inter-assay agreement (number of samples positive in all 3 hrHPV assays; total n = 623) for each age group and cytology classification

From: HPV Prevalence in the Dutch cervical cancer screening population (DuSC study): HPV testing using automated HC2, cobas and Aptima workflows

Age group

Inter-assay agreement

% (N)

Pap class

Bethesda classification

Inter-assay agreement

% (N)

29–33

65.7% (180)

0

-

26.3% (5)

34–38

52.0% (105)

1

Normal

36.2% (339)

39–43

51.0% (103)

2

ASC-US

73.4% (113)

44–48

41.7% (86)

3a1

LSIL

90.8% (59)

49–53

47.7% (72)

3a2

HSIL (moderate)

95.8% (46)

54–58

29.5% (43)

3b

HSIL (severe)

91.8% (56)

59–63

31.8% (34)

4

CIS/AIS

100% (5)

Total (N)

623

  

623

  1. Pap 0 = sample inadequate for cytology
  2. ASC-US Atypical Squamous Cells of Undetermined Significance, LSIL Low-grade Squamous Intraepithelial Lesion, HSIL High-grade Squamous Intraepithelial Lesion, CIS Carcinoma in situ, AIS Adenocarcinoma in situ