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Table 3 Results of multivariate Cox regression analyses for clinicopathological factors and CXCL16 in stromal cells (model 1) and co-expression of CXCL16 in cancer and stromal cells (model 2*)

From: Erratum to: Prognostic impact of CXCL16 and CXCR6 in non-small cell lung cancer: combined high CXCL16 expression in tumor stroma and cancer cells yields improved survival

Factor

HR

CI 95%

P

T-status

  

<0.001 †

 T1

1.00

  

 T2

1.60

(0.97-2.64)

0.065

 T3

3.80

(2.13-6.77)

<0.001

N-status

  

<0.001 †

 N0

1.00

  

 N1

2.01

(1.30-3.11)

0.002

 N2

3.08

(1.74-5.44)

<0.001

Differentiation

  

0.009 †

 Well

1.00

  

 Moderate

1.17

(0.63-2.20)

0.618

 Poor

2.08

(1.12-3.85)

0.020

Performance status

  

0.040 †

 ECOG 0

1.00

  

 ECOG 1

1.52

(1.02-2.26)

0.040

 ECOG 2

2.15

(0.94-4.91)

0.069

Vascular infiltration

   

 No

1.00

  

 Yes

1.70

(1.01-2.87)

0.046

Histology

  

<0.001 †

 Squamous carcinoma

1.00

  

 Adenocarcinoma

2.23

(1.48-3.35)

<0.001

 Large cell carcinoma

0.80

(0.39-1.66)

0.555

CXC16 stromal cells

   

 Low

1

  

 High

0.55

(0.35-0.87)

0.011

CXCL16 cancer and stromal cells*

  

0.031 †

 Low/Low

1.00

  

 Low/High + High/Low

0.57

(0.35-0.93)

0.023

 High/High

0.42

(0.20-0.88)

0.022

  1. †Overall significance as prognostic marker. HR, Hazard ratio. Bold values indicate p < 0.05