Might radiation therapy in addition to chemotherapy improve overall survival of patients with non-oligometastatic Stage IV non-small cell lung cancer?: Secondary analysis of two prospective studies

Table 3 Multivariate analyses for OS in non-oligometastatic patient

Variable	Pre-PSM Cohort				Post-PSM Cohort
	HR	95.0% confidence interval		P value	HR	95.0% confidence interval		P value
	HR	lower	upper	P value	HR	lower	upper	P value
Radiation dose, Gy (<63 vs. ≥63)	1.481	1.071	2.047	0.018	1.656	1.125	2.438	0.011
Response to chemotherapy (No vs. Yes)	1.541	1.092	2.176	0.014	1.643	1.073	2.517	0.022
Post-treatment KPS (Decreased vs. Increased or stable)	1.958	1.319	2.907	0.001	1.704	1.064	2.729	0.026
No. of chemotherapy cycles (≥4 vs. <4)	0.796	0.572	1.106	0.173	-	-	-	-
Gross tumor volume, cm³ (≥146 vs. <146)	1.479	1.082	2.021	0.014	-	-	-	-

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