From: Is immunohistochemistry of BRAF V600E useful as a screening tool and during progression disease of melanoma patients?
Sanger sequencing
Cobas® test
Pyrosequencing
positive
negative
IHC
4
1
23
0
6
2
14
7
Total
15
25
Concordance
85.7% (k = 0.632)
93.1% (k = 0.760)
100% (k = 1)