Table 1 Patients’ characteristics in primary HCC (cohort P) and secondary HCC (cohort S) from mCRC
From: Alternative splicing of estrogen receptor alpha in hepatocellular carcinoma
Clinical features | Cohort P (n = 76) | Cohort S (n = 32) | P value | |
|---|---|---|---|---|
Age (y) | ≤58 | 32 | 13 | 0.887 |
>58 | 44 | 19 | ||
Gender | Female | 39 | 14 | 0.473 |
Male | 37 | 18 | ||
Liver cirrhosis | No | 26 | 31 | 0.000 |
Yes | 50 | 1 | ||
HBsAg | Negative | 17 | 30 | 0.000 |
Positive | 59 | 2 | ||
Preoperative liver function (Child-Pugh) | A | 73 | 32 | 0.553 |
NA | 3 | 0 | ||
AFP | ≤18 ng/ml | 33 | 30 | 0.000 |
>18 ng/ml | 42 | 2 | ||
Tumor size | ≤5 cm | 51 | 26 | 0.138 |
>5 cm | 25 | 6 | ||
Tumor number | Single | 61 | 20 | 0.052 |
Multiple | 15 | 12 | ||
Vascular invasion | No | 63 | 29 | 0.384 |
Yes | 13 | 3 | ||
Pathological Grade | Well | 10 | 0 | NA |
Moderate | 58 | 1 | ||
Poor | 8 | 1 | ||
NA | 0 | 30 | ||
Neo-adjuvant treatments before operation | No | 72 | 28 | 0.233 |
Yes | 4 | 4 | ||
Adjuvant treatments after operation | Yes | 18 | 18 | 0.001 |
No | 58 | 14 | ||
Intra-hepatic recurrence | No | 44 | 29 | 0.001 |
Yes | 32 | 3 | ||
Extra-hepatic metastasis | No | 63 | 26 | 0.838 |
Yes | 13 | 6 | ||
AJCC Stage | 1 | 52 | NA | NA |
2 | 16 | NA | ||
3 + 3A | 8 | NA | ||