| |
Notch1
|
Notch2
|
| |
+
|
−
|
p
|
r
2
|
+
|
−
|
p
|
r
2
|
|
Total (%)
|
66 (50.0)
|
66 (50.0)
| | |
74 (56.1)
|
58 (43.9)
| | |
|
Histopathological grading
|
G1
|
5
|
16
|
0.008
|
0.186
|
10
|
11
|
0.397
|
0.019
|
|
G2/3
|
61
|
50
| | |
64
|
47
| | |
|
Tumor
|
1/2
|
35
|
32
|
0.259
|
0.089
|
36
|
31
|
0.584
|
0.067
|
|
3/4
|
31
|
34
| | |
38
|
27
| | |
|
Node
|
0
|
46
|
46
|
1.000
|
0.000
|
49
|
43
|
0.324
|
0.066
|
|
1
|
20
|
20
| | |
25
|
15
| | |
|
Stage
|
I/II
|
41
|
36
|
0.377
|
−0.086
|
39
|
38
|
0.776
|
0.123
|
|
III/IV
|
25
|
30
| | |
35
|
20
| | |
| |
Notch3
|
Notch4
|
| |
+
|
−
|
p
|
r
2
|
+
|
−
|
p
|
r
2
|
|
Total (%)
|
56 (42.4)
|
76 (57.6)
| | |
8 (6.1)
|
124 (93.9)
| | |
|
Histopathological grading
|
G1
|
5
|
16
|
0.053
|
0.186
|
0
|
21
|
0.090
|
0.161
|
|
G2/3
|
52
|
59
| | |
8
|
103
| | |
|
Tumor
|
1/2
|
34
|
33
|
0.049
|
−0.134
|
5
|
62
|
0.491
|
0.007
|
|
3/4
|
22
|
43
| | |
3
|
62
| | |
|
Node
|
0
|
36
|
56
|
0.247
|
0.091
|
5
|
87
|
0.654
|
0.040
|
|
1
|
20
|
20
| | |
3
|
37
| | |
|
Stage
|
I/II
|
33
|
44
|
0.929
|
0.013
|
4
|
73
|
0.624
|
0.049
|
|
III/IV
|
24
|
31
| | |
4
|
51
| | |
| |
Notch1-3
|
Hes1
|
| |
+
|
−
|
p
|
r
2
|
+
|
−
|
p
|
r
2
|
|
Total (%)
|
106 (80.3)
|
26 (19.7)
| | |
108 (81.8)
|
24 (18.2)
| | |
|
Histopathological grading
|
G1
|
15
|
6
|
0.283
|
0.056
|
16
|
4
|
0.951
|
0.022
|
|
G2/3
|
91
|
20
| | |
92
|
20
| | |
|
Tumor
|
1/2
|
52
|
15
|
0.430
|
0.043
|
54
|
13
|
0.712
|
0.079
|
|
3/4
|
54
|
11
| | |
54
|
11
| | |
|
Node
|
0
|
71
|
21
|
0.156
|
0.119
|
73
|
19
|
0.371
|
0.097
|
|
1
|
35
|
5
| | |
35
|
5
| | |
|
Stage
|
I/II
|
59
|
18
|
0.202
|
0.130
|
60
|
17
|
0.163
|
0.058
|
|
III/IV
|
47
|
8
| | |
48
|
7
| | |
-
P value: χ
2 test
-
r
2 value: Pearson correlation coefficient
