Fig. 4
Immunohistochemical expression of smad4 (left column), smads 6&7 (middle column) and follistatin (right column) in normal colonic mucosa from control (a, b & c), pre-neoplastic lesions from S-AOM group (d to i), adenocarcinoma (j, k & l) and serosal metastatic foci (m, n & o) from the L-AOM group. (Red star = large dysplastic ACF and yellow star = MDF; ×200 magnification, scale bar = 8 μm)