Table 1 Baseline demographic and clinical characteristics

Age, years

<70

≥70

24 (44)

30 (56)

Sex

Male

Female

42 (78)

12 (22)

Etiology

HCV

HBV

Alcohol-related

Unknown

24 (44)

11 (20)

7 (13)

12 (23)

Child-Pugh score, points

5

≥6

33 (61)

21 (39)

TNM staging

III

IV

23 (43)

31 (57)

Vascular invasion

-

+

40 (74)

14 (26)

Maximum tumor size, mm

<50

≥50

33 (61)

21 (39)

Previous therapy

Curative

Other

None

35 (65)

14 (26)

5 (9)

Serum alpha fetoprotein, ng/mL

<100

≥100

25 (54)

29 (46)

DCP, mAU/mL ^a

<1000

≥1000

27 (52)

25 (48)

Initial dose of sorafenib, mg

200

400

600

800

10 (19)

14 (26)

6 (11)

24 (44)