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Table 2 Correlation of CD68+ macrophage with known clinicopathologic characteristics in peritumoral liver tissue and in tumor tissue in 149 HCC cases

From: High-mobility group protein box1 expression correlates with peritumoral macrophage infiltration and unfavorable prognosis in patients with hepatocellular carcinoma and cirrhosis

 

Peri-CD68 expression

Intra-CD68 expression

Features

Low

High

p value

Low

High

p value

Age, year

  ≤ 55

35

56

 

43

48

 

  > 55

32

26

0.034

30

28

0.358

Gender

 Male

40

42

 

39

43

 

 Female

27

40

0.192

34

33

0.412

a-Fetoprotein (ng/ml)

  ≤ 400

46

64

 

55

55

 

  > 400

21

18

0.134

18

21

0.411

Tumor size (mean ± SD, cm)

  ≤ 5

53

69

 

61

61

 

  > 5

14

13

0.280

12

15

0.379

Encapsulation/none

 Complete

38

36

 

39

35

 

 Incomplete

29

46

0.082

34

41

0.231

Tumor differentiation

 I-II

51

64

 

60

55

 

 III-IV

16

18

0.466

13

21

0.109

BCLC stage

 I

54

54

 

49

59

 

 II-III

13

28

0.033

24

17

0.105

Recurrence

 Yes

36

41

 

37

40

 

 No

31

41

0.387

36

36

0.471