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Table 2 Correlation of CD68+ macrophage with known clinicopathologic characteristics in peritumoral liver tissue and in tumor tissue in 149 HCC cases

From: High-mobility group protein box1 expression correlates with peritumoral macrophage infiltration and unfavorable prognosis in patients with hepatocellular carcinoma and cirrhosis

  Peri-CD68 expression Intra-CD68 expression
Features Low High p value Low High p value
Age, year
  ≤ 55 35 56   43 48  
  > 55 32 26 0.034 30 28 0.358
Gender
 Male 40 42   39 43  
 Female 27 40 0.192 34 33 0.412
a-Fetoprotein (ng/ml)
  ≤ 400 46 64   55 55  
  > 400 21 18 0.134 18 21 0.411
Tumor size (mean ± SD, cm)
  ≤ 5 53 69   61 61  
  > 5 14 13 0.280 12 15 0.379
Encapsulation/none
 Complete 38 36   39 35  
 Incomplete 29 46 0.082 34 41 0.231
Tumor differentiation
 I-II 51 64   60 55  
 III-IV 16 18 0.466 13 21 0.109
BCLC stage
 I 54 54   49 59  
 II-III 13 28 0.033 24 17 0.105
Recurrence
 Yes 36 41   37 40  
 No 31 41 0.387 36 36 0.471