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Table 2 Methodology and quality of inclined studies

From: Increased serum amyloid A as potential diagnostic marker for lung cancer: a meta-analysis based on nine studies

Authors Year Research design Country Asians/Caucasians Test method Measurement units QUADAS
Benson MD [12] 1986 Prospective Indiana 0/100 Competitive binding radioimmunoassay u/ml 12
Howard BA [13] 2003 Retrospective USA 0/19 ELISA ng/mL 7
Khan N [14] 2004 NA North Carolina 0/50 MALDI-TOF; ELISA ng/mL 10
Dai S [16] 2007 Retrospective China 175/0 SELDI-TOF-MS; ELISA Peak intensities 9
Liu DH [17] 2007 NA China 275/0 Protein Chip Array Peak intensities 10
Cho WC [15] 2010 Retrospective Hong Kong 189/0 SELDI-TOF; quantitative analysis Peak intensities; ug/mL−1 11
Sung HJ [4] 2011 Retrospective South Korea 380/0 LC-ESI-MS/MS Analysis; ELISA ug/mL 12
Dowling P [18] 2011 Retrospective Ireland 0/109 ELISA ug/mL 10
Kanoh Y [9] 2013 NA Japan 37/0 Latex nephelometry ug/mL 7
  1. QUADAS quality assessment for studies of diagnostic accuracy (maximum score 14); ELISA enzyme-linked immunosorbent assays; MALDI-TOF matrix assisted laser desorption ionization time of flight; SELDI-TOF-MS surface-enhanced laser desorption/inionation-time of flight-mass spectra; LC-ESI-MS/MS liquid chromatography-electrospray ionisation-tandem mass spectrometry NA unavailable