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Table 1 ECM gene signatures in TCGA cancer sets

From: The expression pattern of matrix-producing tumor stroma is of prognostic importance in breast cancer

BRCA COAD COAD cont HNSC KIRC LUAD LUSC
ADAM12 ADAM12 ITGA11 COL1A1 COL1A1 COL1A1 AEBP1
BNC2 AEBP1 LUM COL1A2 COL1A2 COL1A2 COL1A1
CDH11 ANTXR1 MMP2 COL3A1 COL3A1 COL3A1 COL1A2
COL1A1 BNC2 MSRB3 COL6A1 COL5A1 COL5A1 COL3A1
COL1A2 C10orf72 OLFML1 COL6A3 COL5A2 COL5A2 COL5A1
COL3A1 CCDC80 OLFML2B NID2 FAP COL6A3 COL6A3
COL5A1 COL1A1 PCOLCE OLFML2B   THBS2 NID2
COL5A2 COL1A2 PDGFRB PDGFRB    PDGFRB
COL6A3 COL3A1 SPARC POSTN    SPARC
DACT1 COL5A1 THBS2 SPARC    THBS2
FAP COL5A2 THY1 TIMP2    
FBN1 COL6A2 TIMP2 VCAN    
GLT8D2 COL6A3 VCAN     
LUM COL8A1      
POSTN DCN      
SPARC FAM26E      
THBS2 FBN1      
VCAN FSTL1      
  1. The signatures were defined by an iterative process. Starting with the expanded ECM gene set (Additional file 3: Table S3) the gene with the lowest mean value of the correlation coefficients of the log2 expression with the genes in the set was removed from the set. The process was reiterated until all genes had a mean correlation coefficient above 0.85