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Fig. 2 | BMC Cancer

Fig. 2

From: Inhibition of eEF-2 kinase sensitizes human nasopharyngeal carcinoma cells to lapatinib-induced apoptosis through the Src and Erk pathways

Fig. 2

NH125 enhances lapatinib-induced apoptosis in NPC cells. a, b and c CNE-2 and HONE-1 cells were treated with lapatinib (0-5 μM) or DMSO control for 48 h in the presence or absence of 0.25 μM NH125. a Annexin V-APC/7-AAD double staining was performed to detect apoptotic activity. b Cleaved PARP was examined by Western blot analysis. GAPDH was used as a loading control. c Flow cytometry was used to analyse cleaved PARP levels. Results are displayed as histograms. Each bar represents the mean ± standard deviation. *, P<0.05;** and P<0.01

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BMC Cancer

ISSN: 1471-2407

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