Skip to main content

Table 3 Age-stratified analyses of rs2282151 with CRC risk in the discovery, replication stage and combined samples

From: A novel variant on chromosome 6p21.1 is associated with the risk of developing colorectal cancer: a two-stage case-control study in Han Chinese

  

Discovery stage

  

Replication stage

  

Combined

 
 

Case/control

OR (95 % CI)

P a

Case/control

OR (95 % CI)

P a

Case/control

OR (95 % CI)

P a

Age < 50

158/246

1.39 (1.03, 1.88)

0.029

151/390

1.28 (0.97, 1.68)

0.080

309/636

1.33 (1.09, 1.62)

0.006

50 ≤ Age < 70

520/552

1.24 (1.04, 1.48)

0.015

342/143

1.71 (1.22, 2.39)

0.002

862/695

1.33 (1.14, 1.55)

5.2E-4

Age ≥ 70

274/77

1.00 (0.68, 1.47)

0.992

24/16

4.48 (1.43, 14.02)

0.010

298/93

1.17 (0.81, 1.68)

0.405

Combined

952/875

1.24 (1.07, 1.42)

0.003

517/549

1.49 (1.21, 1.84)

1.8E-4

1469/1424

1.31 (1.17, 1.47)

6.2E-6

  1. Abbreviation: OR odds ratio, 95 % CI 95 % confidence interval
  2. aLogistic regression were performed in additive model, adjusted for age and sex
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us