Fig. 1
From: Aldehyde dehydrogenase activity plays a Key role in the aggressive phenotype of neuroblastoma
ALDH1A2 and A3 isoform expression are enhanced during NB self-renewal process. The mRNA expression levels of the three ALDH1 isoforms (ALDH1A1, ALDH1A2 and ALDH1A3) were analyzed by real-time PCR in parental cells (T0) and four sphere passages (s1 to s4) of SK-N-Be2c, NB1-C, and NB1 PDX-derived cells. Data are plotted as ALDH1 mRNA expression relative to the T0 parental cells in pooled s1-s2 and s3-s4 ± SD (unpaired t-test: * correspond to p < 0.05, ** p < 0.01, *** p < 0.0001)