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Table 1 Half maximal inhibitory concentrations (IC50) of anti-folates in Fa2N-4 and Huh7 cell lines

From: Hepatocellular carcinoma-targeted drug discovery through image-based phenotypic screening in co-cultures of HCC cells with hepatocytes

  

IC50(μM)

 

* IC50ER

 

Fa2N-4

 

Huh7

 

MTX

0.01518

 

0.004074

3.726068

Pyrimethamine

23.43

 

2.764

8.476845

Aminopterin

0.001688

 

0.0005194

3.249904

  1. *IC50ER : IC50 with enhancement ratio (Fa2N-4/Huh7)
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BMC Cancer

ISSN: 1471-2407

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