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Table 2 Morphometric parameters and cachexia indicators (a)

From: Leucine-rich diet alters the 1H-NMR based metabolomic profile without changing the Walker-256 tumour mass in rats

Ā 

C (nā€‰=ā€‰9)

W (nā€‰=ā€‰9)

L (nā€‰=ā€‰8)

LW (nā€‰=ā€‰9)

Morphometric parameters

Initial body weight (g)

253.4ā€‰Ā±ā€‰23.5

264.9ā€‰Ā±ā€‰14.6

249.4ā€‰Ā±ā€‰24.7

257.0ā€‰Ā±ā€‰16.5

Carcass weight (g)

247.5ā€‰Ā±ā€‰29.8

184.5ā€‰Ā±ā€‰33.7*, **

243.8ā€‰Ā±ā€‰24.7

188.6ā€‰Ā±ā€‰21.8*, **

Cachexia index (a)

-

63.9ā€‰Ā±ā€‰2.6

-

54.8ā€‰Ā±ā€‰2.9 ***

Tumour weight (g)

-

36.04ā€‰Ā±ā€‰10.2

-

36.82ā€‰Ā±ā€‰9.0

Relative tumour weight (%)(b)

-

14.79ā€‰Ā±ā€‰4.7

-

15.20ā€‰Ā±ā€‰4.8

Serum albumin (g/dL)

2.6ā€‰Ā±ā€‰0.2

1.5ā€‰Ā±ā€‰0.1*

2.7ā€‰Ā±ā€‰0.3

1.6ā€‰Ā±ā€‰0.2*, **

  1. Data are expressed as the meanā€‰Ā±ā€‰SD. Legend: C control; W, tumour-bearing (fed with control diet, 18 % protein); L, control; LW, tumour-bearing (fed with leucine-rich diet, 18 % proteinā€‰+ā€‰3 % leucine). Carcass weight represents the body weight without the weight of the gastrointestinal tract, liver, muscles and tumour. (a)Cachexia indexā€‰=ā€‰[(initial body mass ā€“ carcass massā€‰+ā€‰tumour weightā€‰+ā€‰body mass gain of control)/(initial body massā€‰+ā€‰body mass gain of control)]ā€‰Ć—ā€‰100 %. [1]. (b)Relative tumour weight corresponds to the ratio of tumour and body weights, expressed as a percentage. *Pā€‰ā‰¤ā€‰0.05 in comparison with the C group; **Pā€‰ā‰¤ā€‰0.05 in comparison with the L group; ***Pā€‰=ā€‰0.0561 in comparison to the W group