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Table 4 Multivariate analysis of prognostic factors correlated with outcome

From: With or without reirradiation in advanced local recurrent nasopharyngeal carcinoma: a case–control study

Endpoint

HR (95 % CI)

P value

 OS

  

 Age

0.91 (0.46–1.81)

0.785

 Sex

1.05 (0.45–2.45)

0.920

 rT stage

1.12 (0.60–2.35)

0.618

 rN stage

0.86 (0.40–1.86)

0.701

 EBV DNA

0.67 (0.34–1.32)

0.241

 KPS

2.36 (0.90–6.12)

0.082

 TI

0.89 (0.46–1.72)

0.730

 Significant toxic effects

2.12 (1.01–4.47)

0.047

 Treatment method

0.61 (0.31–1.21)

0.158

TTP

  

 Age

0.60 (0.28–1.29)

0.191

 Sex

0.90 (0.43–1.91)

0.784

 rT stage

1.20 (0.60–2.39)

0.611

 rN stage

1.13 (0.53–2.43)

0.750

 EBV DNA

1.55 (0.73–3.29)

0.251

 KPS

2.10 (0.76–5.81)

0.155

 TI

0.89 (0.46–1.73)

0.730

 Significant toxic effects

1.21 (0.55–2.67)

0.640

 Treatment method

0.49 (0.24–1.02)

0.056

  1. Abbreviations: OS overall survival, TTP time to progression, TI time interval between initial radiation and recurrence, KPS Karnosky performance score, Significant toxic effects Grade3–5 treatment-related late toxicity, Treatment method patients treated with a radiation therapy with or without chemotherapy or chemotherapy alone
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BMC Cancer

ISSN: 1471-2407

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