Table 3 Heterogeneity of c-MYC and ß-catenin with respect to tumor location in advanced CRC (cohort 2)
From: Favorable prognosis in colorectal cancer patients with co-expression of c-MYC and ß-catenin
cMYC IHC | Distant metastasis | LN metastasis | |||
Negative | Positive | Negative | Positive | ||
Primary | Negative | 52 (29.5 %) | 22 (12.5 %) | 23 (20.7 %) | 21 (18.9 %) |
Positive | 58 (33.0 %) | 44 (25.0 %) | 14 (12.6 %) | 53 (47.7 %) | |
cMYC mRNA ISH | Distant metastasis | LN metastasis | |||
Negative | Positive | Negative | Positive | ||
Primary | Negative | 19 (10.8 %) | 20 (11.4 %) | 8 (7.2 %) | 17 (15.3 %) |
Positive | 25 (14.2 %) | 112 (63.6 %) | 17 (15.3 %) | 69 (62.2 %) | |
ß-catenin IHC | Distant metastasis | LN metastasis | |||
Negative | Positive | Negative | Positive | ||
Primary | Negative | 55 (31.3 %) | 14 (8.0 %) | 30 (27.0 %) | 13 (11.7 %) |
Positive | 37 (21.0 %) | 70 (39.8 %) | 16 (14.4 %) | 52 (46.8 %) | |