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Table 4 Factors associated with persistent pain: univariate and multivariate logistic regression models

From: Prevalence of persistent pain after breast cancer treatment by detection mode among participants in population-based screening programs

  Univariate Multivariatea
   95 % CI P-value   95 % CI P-value
  OR Lower Upper   OR Lower Upper  
Detection method (n = 1045)
 Screening Ref.     Ref.    
 Interval 0.6 0.4 0.9 0.017 0.8 0.4 1.4 0.408
Age (n = 1045)         
 50–54 Ref.     Ref.    
 55–59 1.1 0.7 1.9 0.618 1.0 0.5 2.0 0.967
 60–64 0.9 0.5 1.5 0.632 0.7 0.3 1.6 0.424
 65–70 0.7 0.4 1.3 0.282 0.7 0.3 1.7 0.432
Charlson index (n = 1045)
 0 Ref.     Ref.    
 1 2.3 1.5 3.7 <0.001 2.8 1.4 5.4 <0.01
  > =2 3.0 1.8 5.2 <0.001 4.5 2.1 9.5 <0.001
Histological type (n = 1038)
 In situ Ref.     Ref.    
 Ductal 6.4 1.5 26.4 <0.05 0.5 0.1 4.2 0.534
 Lobular 7.6 1.7 34.4 <0.01 1.1 0.5 2.7 0.784
 Other 4.1 0.8 20.5 0.082 0.6 0.2 2.1 0.422
Phenotype (n = 763)         
 Luminal A Ref.     Ref.    
 Luminal B 0.5 0.3 1.1 0.074 0.6 0.3 1.3 0.219
 Her2 0.7 0.3 1.9 0.495 0.8 0.3 2.3 0.713
 Triple negative 1.0 0.5 2.2 0.903 1.1 0.5 2.6 0.800
Axillary treatmentb (n = 983)
 Only SLNB Ref.     Ref.    
 ALND 2.2 1.3 3.7 <0.05 2.0 1.0 4.0 <0.05
Neoadjuvant treatment (n = 1045)
 No Ref.     Ref.    
 Yes 0.5 0.2 1.1 0.095 0.4 0.1 1.3 0.132
Chemotherapy after surgery (n = 1018)  
 No Ref.     Ref.    
 Yes 1.8 1.2 2.8 <0.01 1.4 0.7 2.5 0.334
  1. aN = 704 cases were included in the multivariate analysis. The multivariate logistic regression model included the following variables: detection method, age, Charlson index, histological type, phenotype, axillary treatment, neoadjuvant treatment and chemotherapy after surgery
  2. bSLNB: sentinel lymph node biopsy. In this category only women with SLNB performed were inluded. ALND: axillary lymph node dissection. This category includes women with only ALND performed and women with SLNB and ALND