Fig. 3
From: Changes in the in vitro activity of platinum drugs when administered in two aliquots
Combination Index (CI) values following the administration of a CS, b CB and c OX in two aliquots with a time gap of 2, 4, 8, or 24Â h as applied to the ovarian cancer A2780, A2780cisR, A2780ZD0473R and SKOV-3 cell lines using both fresh/fresh and fresh/aged combinations. CI values were calculated following 72Â h treatments. CI values of <1, =1 and >1 indicate respectively synergism, additivity and antagonism in combined drug action