Table 2 Occurrence of DLTs
AZD3514 dose | Number eligible | Number of DLTs | Proportion that experienced a DLT | Eligible patients experiencing DLT (DLT = D, No DLT = blank) | |||||
|---|---|---|---|---|---|---|---|---|---|
1st | 2nd | 3rd | 4th | 5th | 6th | ||||
250 mg QD | 6 | 0 | 0 % | ||||||
500 mg QD | 6 | 0 | 0 % | ||||||
1000 mg QD | 6 | 1 | 16.7 % | D | |||||
1000 mg BID | 6 | 3 | 50 % | D | D | D | |||
2000 mg BID | 4 | 4 | 100 % | D | D | D | D | - | - |