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Table 1 Common proteins between Hela and SiHa Gal-7+ cell networks

From: Systems-level effects of ectopic galectin-7 reconstitution in cervical cancer and its microenvironment

Name

Process

Model

Reference

CRYAB

Associated with poor prognosis and metastasis, negative regulator of TRAIL-mediated apoptosis, related to hypoxic survival and metastasis

Several

[101–103]

TACSTD2

Correlated with malignant progression, apoptosis resistance and proliferation

Cervical

[104–106]

BCL-3

Negative regulator of apoptosis

Several

[107, 108]

COX19

Biogenesis and regulation of mitochondrial respiratory homeostasis

Several

[109, 110]

OASL

Displays antiviral activity, responsive to type I interferon signal

Several

[111, 112]

CDKN2A

Overexpression is used as a biomarker for progressing lesions

Cervical

[113]

NIBAN/FAM129A

Anti-apoptotic activity

Several

[114–116]

FST

Attenuates rRNA synthesis and trigger FST-mediated apoptosis

Cervical, Breast

[117, 118]

  1. Common regulated proteins in the HeLa and Siha Gal-7+ cell networks and their associated functions in different cancer models