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Table 4 Mean change from baseline and effect size at the end of radiotherapy and 6 months post-radiotherapy

From: Nurse-led group consultation intervention reduces depressive symptoms in men with localised prostate cancer: a cluster randomised controlled trial

   Usual care Intervention Between-groups difference 95 % CI Effect size
  Mean change from baseline 95 % CI Effect size Mean change from baseline 95 % CI Effect size
End of radiotherapy
 HADS Anxiety −0.7 −1.2, −0.3 0.21 −1.0 −1.4, −0.6 0.29 −0.2 −0.8, 0.4 0.09
Depression 0.6 0.3, 0.9 0.21 −0.2 −0.6, 0.1 0.07 −0.8 −1.2, −0.3 0.37
 DT   0.1 −0.3, 0.5 0.05 −0.3 −0.7, 0.2 0.12 −0.4 −0.9, 0.2 0.15
 EPIC-26 Urinary −11.0 −13.4, −8.6 0.68 −9.2 −11.5, −6.9 0.62 1.8 −1.5, 5.1 0.12
Bowel −15.7 −18.4, −12.9 1.34 −12.8 −15.8, −9.8 0.99 2.9 −1.1, 6.9 0.16
Sexual −5.2 −7.9, −2.5 0.18 −2.8 −5.5, −0.2 0.11 2.4 −1.4, 6.1 0.14
Hormonal −1.8 −4.0, 0.3 0.10 0.0 −2.2, 2.2 0.00 1.9 −1.2, 4.9 0.14
 SCNS-SF34-R Physical & daily living 6.0 3.0, 9.1 0.27 6.8 4.0, 9.7 0.37 0.8 −3.3, 5.0 0.04
Psychological −4.1 −6.9, −1.3 0.20 −6.7 −9.4, −4.0 0.32 −2.6 −6.5, 1.3 0.15
Sexuality −3.8 −7.8, 0.2 0.13 −4.9 −9.3, −0.5 0.17 −1.1 −7.0, 4.8 0.04
Patient care and support 0.2 −2.5, 2.9 0.01 −0.8 −3.9, 2.3 0.05 −1.0 −5.1, 3.1 0.05
Health system & information −6.9 −11.0, −2.9 0.23 −7.6 −12.4, −2.8 0.26 −0.7 −6.9, 5.6 0.02
 CaTS Sensory/psychological −0.6 −0.7, −0.5 0.64 −0.7 −0.8, −0.5 0.72 −0.1 −0.3, 0.1 0.10
Procedural −0.7 −0.9, −0.6 0.71 −1.0 −1.1, −0.8 0.86 −0.2 −0.5, −0.02 0.24
6 months post-radiotherapy
 HADS Anxiety −0.6 −1.1, −0.2 0.18 −0.6 −1.1, −0.1 0.18 0.0 −0.7, 0.7 0.01
Depression 0.4 0.04, 0.8 0.16 0.1 −0.3, 0.5 0.04 −0.3 −0.9, 0.2 0.14
 DT   −0.3 −0.6, 0.04 0.14 −0.5 −0.8, −0.2 0.21 −0.2 −0.7, 0.3 0.10
 EPIC-26 Urinary −1.0 −2.9, 0.9 0.06 −2.2 −4.5, 0.1 0.15 −1.2 −4.2, 1.8 0.09
Bowel −6.8 −9.4, −4.3 0.55 −6.2 −8.5, −3.9 0.57 0.6 −2.8, 4.1 0.04
Sexual −4.4 −8.0, −0.9 0.15 −2.1 −5.1, 0.9 0.08 2.3 −2.4, 7.1 0.11
Hormonal −0.8 −3.2, 1.6 0.05 1.3 −1.3, 4.0 0.07 2.2 −1.4, 5.7 0.14
 SCNS-SF34-R Physical & daily living 1.7 −1.4, 4.8 0.07 3.4 0.7, 6.1 0.19 1.8 −2.3, 5.9 0.10
Psychological −7.2 −10.2, −4.3 0.35 −8.0 −10.8, −5.3 0.39 −0.8 −4.9, 3.3 0.04
Sexuality 0.0 −4.6, 4.5 0.00 −1.2 −5.5, 3.1 0.04 −1.2 −7.4, 5.1 0.04
Patient care and support −3.5 −6.1, −1.0 0.20 −1.7 −4.9, 1.5 0.10 1.8 −2.3, 5.9 0.10
Health system & information −10.9 −14.9, −7.0 0.37 −13.4 −17.8, −9.0 0.46 −2.5 −8.4, 3.5 0.09
  1. Effect sizes for changes from baseline = (Mean change from baseline/standard deviation at baseline)
  2. Effect sizes for between-groups differences = ((Intervention Mean change from baseline) – (Usual Care Mean change from baseline)) / pooled standard deviation for change. For HADS, DT, SCNS-SF34-R and CaTS, a score decrease reflects improvement; as such, between-groups differences with a negative sign indicate a greater improvement (or lesser deterioration) among intervention participants. For EPIC-26, a score increase reflects improvement; as such, between-groups differences with a positive sign indicate a greater improvement (or lesser deterioration) among intervention participants