Oligo-recurrence predicts favorable prognosis of brain-only oligometastases in patients with non-small cell lung cancer treated with stereotactic radiosurgery or stereotactic radiotherapy: a multi-institutional study of 61 subjects

Table 2 Characteristics of Patients. Comparing oligo-recurrence with sync-oligometastases

Characteristic	Total No.	Oligo-recurrence group No	Sync-oligometastases group No	p value
Age,
<65	30	24	6	NS
>65	31	26	5	NS
Sex
Male	30			NS
Female	31			NS
No. of metastatic/recurrent lesions
1–2	54	45	9	NS
3–5	7	5	2	NS
Histological status
squamous cell carcinoma	6	5	1	NS
adenocarcinoma	48	40	8
others	7	5	2
KPS score
70–80	5	5	0
90–100	56	45	11
interval to brain recurrence, mo
<12	29	24	5	NS
>12	32	26	6	NS
Neurologic function ^a
grade 0	40	31	7	NS
grade 1	12	10	2
grade2	9	9	0
grade3	0	0	0
grade4	0	0	0
Treatment method for brain tumor
SRS	45	37	8	NS
SRT	16	13	3	NS
WBRT	9	7	2	NS
Thoracic stage ^b
I–II	27	21	6	NS
III	34	29	5	NS
Treatment method for thoracic lesions
Surgery	43	37	6	NS
Radiation therapy	18	13	5	NS
Chemotherapy	19	12	7	NS

Abbreviations: KPS Karnofsky performance status, RPA recursive partition analysis, SRS stereotactic radiosurgery, SRT stereotactic radiotherapy, WBRT whole brain radiation therapy
^aNerologic function, gradeO as no symptoms, grade 1 as minor symptoms: fully active without assistance, grade2 as moderate symptomes; fully active but requires assistance, grade3 as moderate symptoms: less than fully active, requires assistance, grade4 as severe symptoms; totally inactive
^bThoracic stage are classified according to TNM classification of malignant tumors version 6 (UICC, Union for International Cancer Contorol version 6 edition) not evaluating M stage

ISSN: 1471-2407