Performance and prognostic utility of the 92-gene assay in the molecular subclassification of ampullary adenocarcinoma

Table 2 Performance characteristics of the 92-gene classifier for the identification of histological subtypes in ampullary adenocarcinomas

Histopathologic category	N	Type of prediction (N)	Correct predictions	Sensitivity (95 % CI)	Specificity (95 % CI)	PPV	NPV
Ampullary-Intestinal	28	Intestine (18)	18	0.64 (0.46, 0.79)	0.88 (0.70, 0.98)	0.86	0.70
		Pancreaticobiliary (9)
		Gastroesophageal (1)
Ampullary-Pancreaticobiliary	26	Pancreaticobiliary (22)	22	0.85 (0.66, 0.94)	.68 (0.48, 0.84)	0.71	0.83
		Intestine (3)
		Lung adenocarcinoma (1)
Total	54		40	0.74 (0.61, 0.84)

Abbreviations: N number of cases; 95 % CI 95 % confidence interval, PPV positive predictive value, NPV negative predictive value

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