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Table 5 Multivariate Hazard Cox regression analysis of recurrence-free survival considering the categorized combination of both markers

From: MPO density in primary cancer biopsies of ovarian carcinoma enhances the indicative value of IL-17 for chemosensitivity

 

HR

95 % CI

p-values

Age

0.99

0.96–1.02

0.612

MPO + IL17-

0.64

0.17–2.48

0.518

MPO-IL17+

0.26

0.10–0.69

0.006

MPO + IL17+

0.23

0.07–0.73

0.013

Residual disease <2 cm

1.03

0.48–2.20

0.949

Residual disease >2 cm

3.93

1.47–10.52

0.007

N of chemotherapy cycles

1.16

0.89–1.52

0.276

FIGO IIIA

0.08

0.00–1.88

0.115

FIGO IIIB

0.58

0.05–6.48

0.661

FIGO IIIC

0.40

0.04–3.61

0.413

FIGO IV

0.59

0.06–6.00

0.652

  1. Bold data statistically significant p < 0.05
  2. Multivariate analyses showing Hazard Ratios and p-value for all primary cancer biopsies (n = 46 less than 47 due to missing values) conferred by categorized MPO/IL-17 density, age, residual disease after cytoreductive surgery, number of chemotherapy cycles and FIGO classification