From: Prognostic relevance of caspase 8 -652 6N InsDel and Asp302His polymorphisms for breast cancer
Variable | Hazard Ratio | 95Â % CI | P |
---|---|---|---|
Univariate Analysis | |||
 -652 6N del | |||
  InsIns | 1a |  |  |
  InsDel | 1.316 | 0.65–2.68 | 0.450 |
  DelDel | 2.384 | 1.31–5.48 | 0.007 |
Multivariable Analysis | |||
 -652 6N del | |||
  InsIns | 1a |  |  |
  InsDel | 1.490 | 0.72–3.10 | 0.286 |
  DelDel | 2.769 | 1.32–5.81 | 0.007 |
 Age (per year) | 1.002 | 0.98–1.02 | 0.863 |
 Tumor type | |||
  ductal | 1a |  |  |
  lobular | 1.909 | 1.00–3.64 | 0.050 |
  others | 1.713 | 0.88–3.35 | 0.115 |
 Tumor stage | |||
  T1 | 1a |  |  |
  T2-4 | 1.798 | 1.09–2.98 | 0.023 |
 Nodal status | |||
  negative | 1a |  |  |
  positive | 3.681 | 2.13–6.35 | <0.001 |
 Grade | |||
  1 | 1a |  |  |
  2 | 1.044 | 0.56–1.94 | 0.892 |
  3 | 1.776 | 0.89–3.53 | 0.102 |