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Table 1 Summary of pathways associated with volumetric tumor phenotype features of the original volumes (top rows) and their ratios (bottom rows)

From: Imaging-genomics reveals driving pathways of MRI derived volumetric tumor phenotype features in Glioblastoma

  Biological processes (positive correlation) Biological processes (negative correlation)
Volume   
 Necrosis   Immune response, apoptosis
 Contrast Enhancement   Signal transduction
 Edema Homeostasis Cell cycle, proliferation, replication, DNA repair, DNA metabolic process
 Tumor Bulk   Apoptosis, signal transduction, immune system
 Total Volume   Synaptogenesis, biogenesis, extracellular structure organization
Ratios   
 Necrosis/Total Volume   Defense response, immune response, Nf-kB, signal transduction
 Contrast Enhancement/Tumor Volume   Protein complex assembly, signal transduction, biogenesis
 Edema/Tumor Volume Protein complex assembly, defense response, signal transduction, cytokine production, immune response, Nf-kB  
 Tumor Bulk/Tumor Volume   Signal transduction, protein complex assembly, cytokine, immune response, Nf-kB
 Necrosis/Contrast Enhancement   Response to other organism, Nf-kB, immune response, locomotory behaviour
 Contrast Enhancement/Tumor Bulk Response to other organism, Nf-kB, immune response, locomotory behaviour  
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