Fig. 2

Volumetric phenotype features within the same tumor. Detailed example of a glioblastoma tumor in a patient. (a,b) On T1-weighted post-Gadolinium contrast (T1C) images, a central area of Necrosis is typically surrounded by a Contrast Enhancing ring, both of which can be derived from dark and light regions, respectively. Tumor Bulk represents the addition of these tumor features. (c) The Total Tumor Volume is represented by hyperintensity extracted from T2-FLAIR images. Edema is the difference of Tumor Bulk from Total Tumor Volume