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Table 2 Correlations between clinical parameters and the three ALK rearrangement detection methods in all three cohorts

From: Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer

  FISH Ventana IHC Dako IHC
Variable Correlation P-value Correlation P-value Correlation P-value
Gender 0.020 0.601 0.043 0.230 0.078 0.028
Age −0.002 0.959 −0.049 0.167 −0.057 0.108
Stage 0.047 0.197 0.035 0.326 0.042 0.238
Smoking −0.188 <0.001 −0.140 <0.001 −0.166 <0.001
  1. FISH positive vs negative, Ventana IHC Assay intensity 3 vs the other intensities, Dako IHC Assay score <8 vs. ≥8, Age at diagnosis ≤70 years vs. >70 years, Stage IA + IB vs. II-IV, Smoking smokers + ex-smokers vs. never smokers