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Table 2 Correlations between clinical parameters and the three ALK rearrangement detection methods in all three cohorts

From: Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer

 

FISH

Ventana IHC

Dako IHC

Variable

Correlation

P-value

Correlation

P-value

Correlation

P-value

Gender

0.020

0.601

0.043

0.230

0.078

0.028

Age

−0.002

0.959

−0.049

0.167

−0.057

0.108

Stage

0.047

0.197

0.035

0.326

0.042

0.238

Smoking

−0.188

<0.001

−0.140

<0.001

−0.166

<0.001

  1. FISH positive vs negative, Ventana IHC Assay intensity 3 vs the other intensities, Dako IHC Assay score <8 vs. ≥8, Age at diagnosis ≤70 years vs. >70 years, Stage IA + IB vs. II-IV, Smoking smokers + ex-smokers vs. never smokers