Skip to main content

Table 2 Fibrilin-1 expression in TGCTs

From: Fibrillin-1 (FBN-1) a new marker of germ cell neoplasia in situ

  

Fibrilin expression

Histological subtype

N

Mean QS

Standard error of the mean

Median QS

p-valuea

Lowb

Highc

p-valuea

N (%)

N (%)

GCNIS

70

11.30

0.54

12

NA

16 (22.9)

54 (77.1)

NA

SEM

98

6.11

0.49

3

<0.001

73 (74.5)

25 (25.5)

<0.001

EC

94

4.53

0.37

4

<0.001

83 (88.3)

11 (11.7)

<0.001

YST

22

5.59

0.71

6

<0.001

18 (81.8)

4 (18.2)

<0.001

TER

49

3.37

0.49

3

<0.001

46 (93.9)

3 (6.1)

<0.001

ChC

17

0.41

0.23

0

<0.001

17 (100.0)

0 (0.0)

<0.001

Non-neoplastic testis

85

0.02

0.02

0

<0.001

85 (100.0)

0 (0.0)

<0.001

  1. Note that 64 tumours were mixed germ cell tumours (see text)
  2. Abbreviations: GCNIS germ cell neoplasia in situ, NA not applicable, QS multiplicative quickscore
  3. aCompared to GCNIS
  4. bQS 0–9
  5. cQS 10–18
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us