Fig. 5

a Emodin/cisplatin co-treatment significantly increased cell apoptosis in xenograft tumors. In TUNEL assay of transplantation tissues, the cytoplasmic tan and yellow staining represented positive signal for cell apoptosis, and the nucleus were stained by blue. (n = 8). b Emodin/cisplatin co-treatment decreased the expression of MRP1 protein in xenograft tumors. In immunohistochemistry of transplantation tissues, the cytoplasmic tan and yellow staining represented positive protein signal for MRP1 protein, and the nucleus were stained by blue. Scale bar: 60 μm (n = 8)