Fig. 1

Backtracking dasatinib-resistant mutations by DS. Each line represents a patient and each circle corresponds to a sample. Full and empty circles indicate samples with mutations detectable or undetectable by DS, respectively. Light grey filling denotes samples in which the mutation was detectable by DS only. Dark grey filling denotes samples in which the mutation was detectable also by conventional sequencing. For each type of mutation, numbers in parentheses summarize the number of patients in which the mutation could be backtracked by DS/the total number of patients who acquired that type of mutation. Percentages indicate mutation relative abundance. ‘F’ means ‘Failure’, ‘W’ means ‘Warning’, ‘O’ means ‘Optimal’ response; ‘B’ means ‘Baseline’