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Fig. 3 | BMC Cancer

Fig. 3

From: MicroRNA-21 promotes proliferation, migration, and invasion of colorectal cancer, and tumor growth associated with down-regulation of sec23a expression

Fig. 3

MiR-21 inhibits expression of Sec23A in CRC cell lines. a Inhibition of miR-21 expression promoted the expression of Sec23A protein in SW-480 cells relative to negative control (NC) and mock-treated cells (MOCK). b There was no significant difference in expression of Sec23A mRNA in SW-480 cells relative to negative control and mock-treated cells. c-d Over-expression of miR-21 by miR-21 mimic decreased the expression of Sec23A protein and mRNA in DLD-1 cells relative to negative control and mock-treated cells. Protein expression in these cells was determined by densitometric analysis. * p < 0.05, ** p < 0.01

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