Gene-set ID | # of genes | Hits |
p-Value | FDR | Regulation | Transcription factor |
|---|
ATF6_01 | 93 | 34 | 2.23 × 10-5
| 2.69 × 10-3
| up | ATF6 |
XBP1_01 | 152 | 58 | 4.27 × 10-5
| 3.43 × 10-3
| up | XBP1 |
E2F_02 | 96 | 96 | 1.05 × 10-14
| 2.54 × 10-12
| down | N/A |
NFY Q6 | 26 | 16 | 1.06 × 10-3
| 3.65 × 10-2
| down | N/A |
- A ranked list consisting of up- and downregulated genes in HER2/neu-positive SKBR3 cells after palmitate treatment was used as input for a logistic regression pathway analysis (LRPath) to determine enriched transcription factor binding motifs based on the TRANSFAC database. The table shows the two most significantly enriched motifs in the upregulated and downregulated gene groups, as well as the associated transcription factors. N/A indicates that no known transcription factor is associated with this particular motif
