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Table 1 Edmondson-Steiner grade

From: Gd-EOB-DTPA-enhanced magnetic resonance imaging combined with T1 mapping predicts the degree of differentiation in hepatocellular carcinoma

Edmondson-Steiner grade  
I Cells with abundant cytoplasm and minimal nuclear irregularity
II Greater nuclear irregularity and prominent nucleoli
III Increased nuclear pleomorphism and angulation of the nuclei; Tumour giant cells were also more commonly seen
IVa Poorly differentiated with marked nuclear pleomorphism, hyperchromatism and anaplasia
  1. aLimited by study population, this study did not include HCC of Edmondson-Steiner grade IV