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Fig. 3 | BMC Cancer

Fig. 3

From: Saikosaponin d induces cell death through caspase-3-dependent, caspase-3-independent and mitochondrial pathways in mammalian hepatic stellate cells

Fig. 3

SSd induced cytotoxicity accompanied by an increase in caspase-3/7 and caspase-9 activity. (a) After treatment with serial concentrations of SSd for 24 h, cell survival of, cytotoxicity against, and caspase-3/7 activity in HSC-T6 cells were detected by an ApoTox-Glo™ Triplex assay kit. Caspase-9 activity was detected by a Caspase-Glo® 9 assay kit. (b) The same experiments described were performed in LX-2 cells. The data are the mean ± S.D. from 3 independent experiments

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