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Table 2 Summary of in-frame gene fusions

From: Transcriptome analysis of paired primary colorectal carcinoma and liver metastases reveals fusion transcripts and similar gene expression profiles in primary carcinoma and liver metastases

5′ Gene Location Direction 3′ Gene Location Direction Chimera class Cancer type Patients no.a
GTF2E2 chr8:30510950 - NGR1 chr8:32585467 + intrachromosomal complex   1 (PC, LM)
TMEM66 chr8:29940363 - NGR1 chr8:32453346 + intrachromosomal complex Identical patient 4 (PC, LM)
TNNC2 chr20:44452630 - WFDC3 chr20:44404241 - intrachromosomal complex 3 (PC, LM)
HEPHL1 chr11:93800911 + PANX1 chr11:93862496 + intrachromosomal_NGb   3 (PC, LM)
KIAA1984 chr9:139701518 + C9orf86 chr9:139717977 + intrachromosomal_NG Common fusion 3 (LM); 4 (PC)
SLC39A1 chr1:153933048 - CRTC2 chr1:153927642 - intrachromosomal_NG 2 (PC); 4 (LM)
SCNN1A chr12:6457893 - TNFRSF1A chr12:6443410 - intrachromosomal_NG 3, 5 (PC); 1 (LM)
RUVBL1 chr3:127823674 - LDHA chr11:18424445 + interchromosomal complex   2 (PC)
TPT1 chr13:45914237 - YBX1 chr1:43149117 + interchromosomal complex   3 (PC)
ZMYND8 chr20:45976600 - SEPT9 chr17:75398141 + interchromosomal complex   3 (PC)
SOLH chr16:583998 + NOC4L chr12:132635526 + interchromosomal complex   4 (PC)
CALR chr19:13054619 + EEF2 chr19:3981399 - intrachromosomal complex   5 (PC)
DDX27 chr20:47855837 + ZNFX1 chr20:47855592 - intrachromosomal complex   3 (PC)
KIF3B chr20:30865568 + WFDC12 chr20:43752906 - intrachromosomal complex   1 (PC)
GSK3B chr3:119720893 - POLQ chr3:121155122 - intrachromosomal complex   1 (PC)
CKLF chr16:66597120 + CMTM1 chr16:66611007 + intrachromosomal_NG Primary specific 2 (PC)
DUS4L chr7:107217037 + BCAP29 chr7:107221204 + intrachromosomal_NG   1 (PC)
HSPE1 chr2:198367852 + MOBKL3 chr2:198388348 + intrachromosomal complex_NG   2 (PC)
PRIM1 chr12:57127931 - NACA chr12:57118307 - intrachromosomal complex_NG   4 (PC)
RNF43 chr17:56494378 - SUPT4H1 chr17:56428869 - intrachromosomal_NG   4 (PC)
SLC10A3 chrX:153716020 - UBL4A chrX:153714672 - intrachromosomal_NG   4 (PC)
UBA2 chr19:34957919 + WTIP chr19:34981281 + intrachromosomal_NG   5 (PC)
ZNF606 chr19:58499575 - C19orf18 chr19:58485571 - intrachromosomal_NG   4 (PC)
HSP90AA1 chr14:102551123 - NOP58 chr2:203165075 + interchromosomal complex   1 (LM)
RPS15A chr16:18794368 - RPL0 chr8:99057311 - interchromosomal complex   4 (LM)
FGG chr4:155526082 - ALB chr4:74285288 + intrachromosomal complex   2 (LM)
ACE2 chrX:15582147 - PIR chrX:15509432 - intrachromosomal complex Liver metastases specific 3 (LM)
OAF chr11:120097705 + POU2F3 chr11:120117158 + intrachromosomal_NG   2 (LM)
SENP3 chr17:7474797 + EIF4A1 chr17:7477578 + intrachromosomal_NG   4 (LM)
TGIF2 chr20:35207369 + C20orf24 chr20:35236118 + intrachromosomal_NG   1 (LM)
  1. aPatients No.: PC primary carcinoma, LM livermetastases
  2. b NG neighboring gene between the 5′ and 3′ fusion partner