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Table 1 Characteristics of ESCC cases and controls

From: Single nucleotide polymorphism rs13042395 in the SLC52A3 gene as a biomarker for regional lymph node metastasis and relapse-free survival of esophageal squamous cell carcinoma patients

Variables SNP and ESCC risk SNP and ESCC progression SNP and ESCC prognosis
ESCC (N = 479) Control (N = 479) ESCC (N = 343) ESCC (N = 288)
Gender
 Female 109 109 87 79
 Male 370 370 256 209
Age (years) (M ± SD) 59.92 ± 9.34 59.61 ± 8.84 58.39 ± 8.83 58.28 ± 8.84
Size of tumor (cm)
 ≤3 101   98 89
 4–5 160   158 130
 ≥6 89   87 69
 Unknown 129   0 0
Depth of tumor invasion
 Tis 8   8 5
 T1 29   29 24
 T2 45   45 39
 T3 239   239 216
 T4 22   22 4
 Unknown 136   0 0
Regional lymph node metastasis
 N0 178   178 150
 N1 103   103 88
 N2 40   40 34
 N3 22   22 16
 Unknown 136   0 0
Distant metastasis
 M0 337   337 288
 M1 6   6 0
 Unknown 136   0 0
Tumor location
 Upper thoracic 56   27 19
 Middle thoracic 251   191 158
 Lower thoracic 143   125 111
 Unknown 29   0 0
TNM classification
 0 8   8 4
 I 42 (3)a   39 35
 II 156 (18)a   138 124
 III 185 (33)a   152 125
 IV 20 (14)a   6 0
 Unknown 68   0 0
Radiotherapy after surgery
 No    204 204
 Yes    84 84
 Unknown    55 0
Chemotherapy after surgery
 No    207 207
 Yes    81 81
 Unknown    55 0
  1. All associations are significant at P < 0.05
  2. ESCC esophageal squamous cell carcinoma, SNP single nucleotide polymorphism, M mean, SD standard deviation
  3. aData shown in parentheses represent patients without tumor resection